Fractionation Ethyl Acetate Extract of Stem Bark Soursop(a. Muricata. Linn) Potential Anticancer

Pince Salempa(1*), Muharram Muharram(2), Iwan Dini(3),

(1) 
(2) 
(3) 
(*) Corresponding Author



Abstract


Influence the toxicity of the ethyl acetate extract of the bark of the soursop (Annona muricata. Linn) at Brine Shrimp Lethality Test Test (BLST) against Artemia salina. The test is to observe the lethal concentration of one of the active fraction. Fractionation and characterization is done by thin layer chromatography, liquid chromatography column vacuum (KKV) and column chromatography press (of the summit). The ethyl acetate extract on one of the main fraction showed activity with LC50 value is 16.688 ppm.

Keywords: soursop, A. muricata Linn., Toxicity, Artemia salina

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